Hotel Galles Roma is right in front of the National Library, near the Umberto I Hospital and La Sapienza University.
Very close to the hotel you will find:
If you arrive by air: from Fiumicino's "Leonardo da Vinci" airport you may take the Leonardo Express. Otherwise you may use the shuttle bus or public taxi service. From Ciampino Airport there are several frequent and convenient bus services.
If you arrive by car: from the Grande Raccordo Anulare (the Great Ring Road, or GRA) follow signs to the city centre and to Termini Station.
Termini Station is also the terminus of many bus and tram routes that lead to most of Rome's central areas and its outskirts, as well as of the "Open Bus" tourist lines allowing you to go through the most interesting tourist and social venues.